This is a Kouja no Senshi adaption of the infamous old point and click game from Lucasarts.
The former heroes partake on a rescue mission with some other students and a few familiar faces to rescue Sandy, Princess, Kenichi, and Miss Whoops from the evil Meteor and the Edisons!
- Antagonists: Dr. Fred Edison, Purple Tentacle, and Evil Meteor
- This is chronologically the first side story to take place after the end of Day of Destiny Arc.
- Serena, Amy, Raye, Lita, Mina, Julayla, Fuzzy, Darian, Ami, Yumi, Princess, Vultureman (as Kenichi), Jake Long, Betty, Danny, June, Jenny Wakeman, Cherry, Berry, the Powerpuff Girls, and Rowdyruff Boys all remeet each other for the first time, despite lack of past memories.
- This is the first cameo appearances of the reincarnations of Queen Beryl and the 4 Generals: Kuin Beryl, Tidus Jade, Maxfield Stanton, Sylvia Zoi, and Kite Malice.
- The Powerpuff Girls and Rowdyruff Boys become permanently like their Demashita! Powerpuff Girls Z counterparts (mostly in body only).
- This is the first time they meet Bernard. They won't remeet him again until Day of the Tentacle~KNS Style.